Found 11 matching trials
Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge Infection
PHASE2This study evaluates the efficacy, safety and immunogenicity of different f...
Location
George Washington University
Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae
PHASE1An experimental hookworm infection model is being developed to provide earl...
Location
George Washington University Medical Faculty Associates
Repeated Controlled Human Hookworm Infection
NATwenty-four healthy hookworm-naive volunteers will be exposed to 50 L3 Neca...
Location
Leiden University Medical Center
Hookworm Therapy for Coeliac Disease
PHASE1This trial is a Phase 1b multicentre, multinational, randomized, double-bli...
Location
Prince Charles Hospital
Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center
NAFour healthy hookworm-naive volunteers will be exposed to 50 L3 Necator ame...
Location
Leiden University Medical Center
Desensitising Celiac Disease Patients With the Human Hookworm
PHASE1We have established that the hookworm Necator americanus (Na) dramatically ...
Location
Prince Charles Hospital
Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity
PHASE2The disappearance of intestinal parasites from humans in developed countrie...
Location
Queensland Institute of Medical Research
Immune Responses in the Skin After Hookworm Infection
NAFive healthy volunteers will be repeatedly exposed to L3 Necator americanus...
Location
Leiden University Medical Center
Immunoregulation by Controlled Parasite Exposure in Multiple Sclerosis.
PHASE2The aim of the study is to determine whether controlled infection with a cl...
Location
Nottingham University Hospital NHS Trust
Immunisation, Treatment and Controlled Human Hookworm Infection
NA24 healthy volunteers will be immunized with three times 50 L3 larvae or pl...
Location
Leiden University Medical Center